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Nanoantioxidant/Antioxidant Therapy in 2019-nCoV: A New Approach to Reactive Oxygen Species Mechanisms

[ Vol. 16 , Issue. 4 ]

Author(s):

Ali Fathi Jouzdani, Rezvan Heidarimoghadam, Maryam Hazhirkamal and Akram Ranjbar*   Pages 291 - 298 ( 8 )

Abstract:


The COVID-19 pandemic has caused serious concerns for people around the world. The COVID-19 is associated with respiratory failure, generation of reactive oxygen species (ROS), and the lack of antioxidants among patients. Specified ROS levels have an essential role as an adjuster of immunological responses and virus cleaners, but excessive ROS will oxidize membrane lipids and cellular proteins and quickly destroy virus-infected cells. It can also adversely damage normal cells in the lungs and even the heart, resulting in multiple organ failures. Given the above, a highly potent antioxidant therapy can be offered to reduce cardiac loss due to COVID-19. In modern medicine, nanoparticles containing antioxidants can be used as a high-performance therapy in reducing oxidative stress in the prevention and treatment of infectious diseases. This can provide a free and interactive tool to determine whether antioxidants and nanoantioxidants can be administered for COVID-19. More research and studies are needed to investigate and make definitive opinions about their medicinal uses.

Keywords:

Antioxidants, COVID-19, nanoantioxidant, reactive oxygen species, mitochondria, organelles.

Affiliation:

Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Nutrition Health Research Center, Hamadan University of Medical Sciences, Hamadan

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